Plague Inc. Wiki

The USA (short for the United States of America) is a rich country with a balanced climate. It shares a land border with Canada and Mexico, and has around 316 million people in-game, and can be very easy to infect because of the many airport links it has, linking with every country in the map with an airport.

Country Information

IG Factbook: "Britain's American colonies broke with the mother country in 1776 and were recognized as the new nation of the United States of America following the Treaty of Paris in 1783. During the 19th and 20th centuries, 37 new states were added to the original 13 as the nation expanded across the North American continent and acquired a number of overseas possessions. The two most traumatic experiences in the nation's history were the Civil War (1861-65), in which a northern Union of states defeated a secessionist Confederacy of 11 southern slave states, and the Great Depression of the 1930s, an economic downturn during which about a quarter of the labor force lost its jobs. Buoyed by victories in World Wars I and II and the end of the Cold War in 1991, the US remains the world's most powerful nation state. Since the end of World War II, the economy has achieved relatively steady growth, low unemployment and inflation, and rapid advances in technology."


Airport Links

The USA has air routes with all countries with an airport. These countries include: Australia, Brazil, Canada, China, Egypt, France, Germany, Iceland, India, Indonesia, Italy, Japan, Mexico, New Zealand, Russia, Saudi Arabia, South Africa, Spain, and the UK.

Seaport Links

The USA has sea routes with six countries: Brazil, Caribbean, C. America, Egypt, Russia, and the UK.


  • As the USA is a rich country with a balanced climate, it is not required to evolve abilities such as Heat Resistance 1 and Cold Resistance 1 in order to excel in this country. Like other rich countries, the United States has a well-funded health care system, and thus it is inadvisable to start in the country, as it may take an incredibly long time to infect even a small population.  The only definite exception to this rule is if the player wants to win achievements for DarkWater when playing as the Necroa Virus. Nevertheless, it is imperative that that the player purchases Drug Resistance 1, as well as Drug Resistance 2 in Mega Brutal and Brutal difficulties.


  • If the player starts in the USA while playing the Necroa Virus, the game may say that a company named DarkWater created the Necroa Virus; a fictional American research team.
  • If the player starts in this country in the Fake News scenario, the player can unlock the Independence Day achievement, which is a reference to a movie filmed in the United States.
  • Between 2016 and 2020, several news headlines about the 45th President of the United States, Donald Trump were added to the game. These are:
    • "US President buys Condo in Greenland - claims victory" referring to the Trump administration's attempted purchase of the island from Denmark.[1]
    • "Kim and Don livestream Fornite from Singapore", referring to the 2018 North Korea–United States Singapore Summit. Also, at the time this news was added, it was very popular to do a Fortnite livestream.[2]
    • "Child tells President that 'injecting disinfectant is Not Good'" referencing the time Donald Trump in a 2020 speech said about infecting disinfectant as a measure to prevent diseases.[3]
  • In December 2019 the Armageddon expansion for Plague Inc. The Board Game was released, in which Tomorrow's World cards were introduced for some countries, among them, a card was added with the United States going through an isolationist period,[4] meaning that this country no longer has access to any transport links such as airports or seaports.[5]
  • Despite Alaska being part of the United States, it is actually part of Canada in Plague Inc. Alaska is not part of the USA anymore, as the Canadians somehow acquired it via a treaty called the "Hay-Herbert Treaty." This was a joke put in by the game designers because an error in the game made it impossible for Alaska to be part of the USA.
    • Also, Hawaii does not appear on the map, because small islands are not included in the game.


United States Country Card with the cities of Washington D.C., New York, Los Angeles, Chicago, Houston, Philadelphia & Phoenix
Territory: 9,147,420 (km2)
Population: 318,9 (m)
Resources: $7,419 (bn)
United States Country Card with the cities of Washington D.C., New York, Los Angeles, Chicago, Houston, Philadelphia & Phoenix
Territory: 9,147,420 (km2)
Population: 318,9 (m)
Resources: $7,419 (bn)


  1. Finnegan, Conor (2020-04-23). "After Trump tried to buy Greenland, US gives island $12M for economic development". ABC News Retrieved on April 18, 2022.
  2. "Trump says he and Kim are ‘going right now for a signing’" (2018-06-11). CNBC Retrieved on April 18, 2022.
  3. "Coronavirus: Outcry after Trump suggests injecting disinfectant as treatment" (2020-04-24). BBC Retrieved on April 18, 2022.
  4. Nieva, Jason (2019-04-19). "Plague Inc.: The Board Game's Armageddon Expansion Now On Kickstarter". Retrieved on April 25, 2022.
  5. "Plague Inc: Armageddon Expansion". Kickstarter Retrieved on May 3, 2022.
Countries in Plague Inc.
Africa AlgeriaAngolaBotswanaEgyptLibyaMadagascarMoroccoSouth AfricaSudanZimbabweCentral AfricaEast AfricaWest Africa
Asia AfghanistanChinaIndiaIndonesiaIranIraqJapanKazakhstanKoreaPakistanPhilippinesSaudi ArabiaCentral AsiaMiddle EastS.E Asia
Europe FinlandFranceGermanyIcelandItalyNorwayPolandRussiaSpainSwedenTurkeyUKUkraineBalkan StatesBaltic StatesCentral Europe
North America CanadaGreenlandMexicoUSAC. AmericaCaribbean
South America ArgentinaBoliviaBrazilColombiaPeru
Oceania AustraliaNew GuineaNew Zealand