Symptom Combos are special combinations of Symptoms (and in some cases Transmission traits or Abilities) that can affect the plague's Core stats or climate resistances, as well as trigger special events which can slow or speed up Cure progression, or draw attention to the disease. All combos have an achievement associated with them.
Note that it seems to take a while for symptom combos to appear and take effect. Please also note that the list may not be complete. Please feel free to add to the list.
To achieve a combo, one must evolve two or more different symptoms. They range from two tier 1 symptoms to eight symptoms and two infections, so using them is a viable strategy for new players and advanced players alike.
Also be aware that once a combo has been triggered, it is not reversible and remains in effect even if you devolve the traits that caused it to trigger.
|Projectile Vomiting||Increases infectivity|
|Walking Dead||Decreases Cure research rate|
|Profuse Bleeding||Slightly increases lethality, greatly increases infectivity|
Lowers productivity but draws attention to the plague.
|Public Defecation||Increases infectivity and draws attention to disease. Increases research speed.|
|Swine Flu||Slight increase in work needed for a Cure. 10% increase in budget required for cure.|
|Increases Severity, Infectivity, and Lethality.|
|Tank||Slight Severity boost|
|Spitter||Slight Severity boost|
|Boomer||Slight Severity boost|
|Walking Contradiction||Slight Severity decline||Photophobia, Cathemeral Shift|
|Runner||Slight Severity boost|
|Bath Time||Infectivity Boost|
|Assassin||Increases Ape combat abilities|
|Blind Genius||Increases Cure Production|
|Discovery Channel||Increases Ape to Ape transmission|
Increases cross-species transmission
|Red Ape Redemption||Increases Ape combat abilities|
|Rude Awakening||Increases Ape to Ape transmission|
|Zombie Panic||Slows Research Speed|
|Bat Cave||Bat 3|
|Plague Dogs||Increases Infectivity||Dog 2|
|Essential Vitamins||Increases Infectivity|
|Diamond Skin||Increases Infectivity and Severity||Anaemia|
|Welcome to Hellmouth||Increases Deaths/Second for Blood Rages||Demonic Fury|
|Carpe Jugulum||Steroidal Boost|
|Blood Trumps All|
|Evil Is A Point Of View||Decreases Strength of Templars and of Government Actions|
|Uphill Ice Skating||Increases Deaths/Second for Blood Rages in Cold climates||Extreme Bioaerosol|
|Silent but Deadly||Increases Severity|
|Dark Knight||Increases Deaths/Second for Blood Rages|
|Mr. Universe||Increases Infectivity|
|Symptom Combos in Plague Inc. and Plague Inc: Evolved.|
|Assassin ● Bath Time ● Blind Genius ● Blood in the Air ● Boomer ● Carpe Jugulum ● Cranial Dispersion ● Discovery Channel ● Fly Magnet ● On The Naughty List ● Oops ● Profuse Bleeding ● Projectile Vomiting ● Public Defecation ● Red Ape Redemption ● Red Rain ● Rude Awakening ● Runner ● Spitter ● Swineflu ● Symptom Combos ● Tank ● Ultimate Christmas ● Vampire Bat ● Walking Contradiction ● Walking Dead ● Zombie Panic|
|Achievements in Plague Inc. and Plague Inc: Evolved.|