"Patient Zero is infected with a new mutated strain of the Influenza A (H1N1) virus. It is a reassortment of the 2009 strain with limited lethality - existing anti-virals are moderately effective against it. However, analysis of its genetic makeup has identified potential sequence similarities to the 1918 'Spanish Flu' strain that killed 5% of the world's population. Will history repeat itself?" - Plague Inc., Swine Flu introduction paragraph
The Swine Flu is a scenario.
Contents
Transmissions
Zoonosis Transmissions
These Transmissions are available right at the start of the game without evolving other traits.
Swine 1 | Pathogen uses pigs as prime host for antigenic shift - exchanging genes with multiple strains of influenza. (Note: Already evolved at the start of the game.) |
Swine 2 | Pigs more susceptible to infection by pathogen crossing species barrier. Increases infectivity, particularly in rural areas. |
Livestock 1 | Livestock susceptible to infection. Increase infectivity, especially in rural regions and mutation. |
Livestock 2 | Wildlife susceptible to infection. Increase infectivity, especially in rural regions and mutation. |
Bird 1 | Birds becom susceptible to infection. Avian carriers increase infectivity, land transmission and mutation. |
Bird 2 | Avian brain tissue compromised causing birds to attack other species. Increases mutation, infectivity and land based transmission. |
Extreme Zoonosis | Infection crosses multiple species barriers. Increases infectivity, especially in rural and urban areas, mutation chance and cross-country transmission. |
Bioaerosol Transmissions
These Transmissions are available to right at the start of the game without evolving any other traits.
Air 1 | Gives pathogen ability to travel on dust particles. Increases infectivity, especially in arid environments and plane transmission. |
Air 2 | Gives organism ability to survive suspended in air for a long time. Increases infectivity, especially in arid environments and plane transmission. |
Water 1 | Pathogen can survive outside the body in fresh, warm water. Increase infectivity, especially in humid environments and ship transmission. |
Water 2 | Pathogen able to survive in chemically treated water. Increase infectivity, especially in humid environments and ship transmission. |
Extreme Bioaerosol | Pathogen bypasses air/water filters due to adaptive cellular shell. Increase infectivity, especially in humid & arid climates and plane/ship transmission. |
Droplets Transmissions
These Transmissions are available to you right at the start of the game without using any DNA points.
Droplets 1 | Pathogen suspended in expelled liquid particles from victim. Increase infectivity, especially on planes. |
Droplets 2 | Pathogen able to survive for longer in expelled droplets. Increase infectivity, especially on planes. |
Blood 1 | Gives organism ability to spread through blood-to-blood contact. Increases infectivity, especially in poor regions and mutation chance. |
Blood 2 | Infected bodily fluids able to pass through mucous membranes. Increases infectivity, especially in poor regions and mutation chance. |
Symptoms
H1N1 Flu Symptoms
These are the Symptoms that are available to the player right at the start of the game without using any DNA points.
Tier 1 | |
Nausea | Irritated stomach lining leads to discomfort. Slight chance of infection when kissing. |
Coughing | Chance of infection by spreading pathogen into surroundings, especially in high density urban areas. (Note: Already evolved from the start of the game.) |
Pharyngitis | Sore throat causes discomfort and increases likelihood that coughing will spread disease. (Note: Already evolved from the start of the game.) |
Rash | The skin becomes blistered and painful, slightly increasing infectivity. |
Insomnia | Inability to sleep makes people irritable and less productive. |
Tier 2 | |
Vomiting | The expulsion of infected material through projectile vomiting increases the risk of infection. |
Pneumonia | Serious fluid build and discharge from the lungs. People in cold climates especially vulnerable. (Note: Already evolved from the start of the game.) |
Sneezing | Fluid discharge through sneezing greatly increases infection rates. (Note: Already evolved from the start of the game.) |
Inflammation | Inflammation obstructs bodily processes. Swelling can obstruct breathing and be fatal. |
Paranoia | Irrational delusions and mental symptoms. Victims distrust of others makes them unlikely to seek treatment or cooperate with others. |
Fatigue | Extreme tiredness makes people weaker and less productive. |
Tier 3 | |
Pulmonary Oedema | Potentially fatal heart abnormality causes breakdown of respiratory system, releasing pathogen into the air. |
Hyper sensitivity | Increases likelihood of allergic reactions which can distract the immune system. Rich regions particularly vulnerable. |
Headache | Strong headache behind the eyes causes discomfort and reduces ability to work. (Note: Already evolved from the start of the game.) |
Tier 4 | |
Diarrhoea | Pathogen active in digestive tract, causing infection through faeces and potentially lethal dehydration. Poor countries very vulnerable. |
Pulmonary Fibrosis | Scarring of the lungs causes shortness of breath and extreme coughing. Can be fatal when combined with intense exercise. |
Pulmonary Embolism | Blockage in the pulmonary artery prevents blood from reaching the lungs. Severe and potentially fatal. |
Myocarditis | Infection inflames and damages heart muscles. Severe and potentially fatal. |
Tier 5 | |
Dysentery | A complete breakdown in the digestive system causes infected sewage, dehydration, starvation and death. |
Systemic Infection | Pathogen affects multiple organs and tissue types, causing body-wide infections that spread fast and can be fatal. |
Coma | Neuropathic effects in the brain stem causes loss of consciousness and sometimes death. Significantly harder to cure. |
Immune Suppression | Pathogen attach to lymphocytes, suppressing immune system and allowing significantly greater freedom of mutation. Can be lethal. |
Fever | Increase in temperature, contagiousness and severe dehydration, which can be fatal. (Note: Already evolved from the start of the game.) |
1918 Spanish Flu Symptoms
These Symptoms can only be taken by first taking the 'Historic Reassortment' ability, available at the start of the game.
Tier 1 | |
Epistaxis | Haemorrhage of the nasal mucous membranes causes severe nosebleeds. |
Tier 2 | |
Haemoptysis | Coughing up blood from inflames bronchi increases infectivity and is fatal in extreme cases. |
Haemorrhagic Shock | Severe loss of blood volume causes oxygen deprivation, loss of consciousness and death. |
Tier 3 | |
Pulmonary Haemorrhage | Severe bleeding through the lungs increases infectivity and can result in asphyxiation. |
Tier 5 | |
Total Organ Failure | Catastrophic cell death of multiple tissue types causes body-wide organ failure and rapid death. |
Cytokine Storm | Positive feedback loops between cytokines and immune cells causes fatal immune reaction. Can offer insights into cure development. |
Abilities
Climate Abilities
These abilities will affect the plague in different countries, climates and temperatures.
Cold Resistance 1 | Pathogen evolves to withstand cold temperatures and climates. |
Cold Resistance 2 | Lower intracellular water volume prevents freezing. Increased effectiveness in cold climates |
Heat Resistance 1 | Pathogen evolves to withstand hot temperatures and climates |
Heat Resistance 2 | Pathogen avoids cellular breakdown in high temperatures. Increased effectiveness in hot climates. |
Environmental Hardening | Pathogen develops hardened coating - becoming highly weather resistant and extremely comfortable in both hot and cold climates. |
Cure/Drug Resistance Abilities
These abilities will affect the plague's resistance against treatments and drugs. They will also slow down cure creation speed and increase more work required to create a cure.
Drug Resistance 1 | Pathogen becomes resistant to class 1 and 2 antibiotics. Increase effectiveness in wealthy countries. |
Drug Resistance 2 | Pathogen develops resistance to class 3 and 4 antibiotics. Increase effectiveness in wealthy countries. |
Genetic Hardening 1 | Pathogen becomes harder to analyse in the lab. Decreases future research speed. |
Genetic Hardening 2 | The pathogen does not reproduce in lab conditions. Decreases future research speed. |
Genetic ReShuffle 1 | Pathogen DNA strands reassembled. More work needed to develop a cure. |
Genetic ReShuffle 2 | A new strain of the pathogen now exists, increasing the work needed to develop a cure. |
Genetic ReShuffle 3 | Multiple strains of the pathogen now exists, increasing the work needed to develop a cure. |
Unique Abilities
These are abilities exclusive to the plague, Swine Flu
Viral Instability 1 | DNA becomes more unstable, increasing random mutations. |
Viral Instability 2 | DNA occasionally fractures, increasing random mutations. |
Viral Instability 3 | DNA becomes highly erratic and fragmented, increasing random mutations. |
Bacterial Pneumonia | Pathogen damages pulmonary lining, allowing lethal secondary bacterial infections. Antibiotics will reduce impact. |
Historic Reassortment | Gives ability to access the genetic sequence in the 1918 flu. Highly lethal strain. |
Scenarios in Plague Inc. and Plague Inc. Evolved |
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