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The following are strategy guides for the Where Is Everyone? scenario. Please feel free to add your own strategy, advice, and Q&A below:

Strategy 1[]

Note: This strategy uses the Shadow Plague. It can work on any difficulty. Do not evolve Shadow Blessing since you just need the active abilities.

Genetic Code:

1. Start in Australia, and immediately evolve Blood Rage and Therianthropy. Use Blood Rage quickly.

2. Due to the drastic decrement to world population without any effect on Vampire's killing rates, Blood Rage will empty the country at an exceptional rate, causing the Vampire to starve. Once Australia has been destroyed, fly to the northern area of New Zealand. When possible, evolve Travel Speed 1.

3. Keep moving as you drain countries dry. It won't take long for the Templars to notice your purge and mobilize to stop you. Once you get a popup saying that the Templars are taking steps to eliminate vampires, keep a sharp eye out.

4. Once the Templar Bases appear, target them for destruction. The most efficient method of exterminating the Templar Bases is to completely drain the countries they are located in. Evolve your way up to Demonic Fury if necessary, though this is unlikely. Do this until the Bases are eliminated. If your vampire is low on health, evolve Dark Ritual 1. It's unlikely that you will need to evolve Lair since the Vampire be constantly on the move, healing all the while.

5. Once the Templars have been eliminated, simply destroy all countries using Blood Rage. Within 3 in-game years, you will have eliminated all human life. Congratulations.

DiseaseMaster7

Strategy 2[]

Difficulty: 3-biohazards on Mega Brutal

Disease: Virus

This strategy is basically a speed run of Virus - since we don't get a lot of DNA in this scenario, we want some free mutations to advance us. For me, this worked 5/6 times.

Note: This strategy relies slightly on luck since we are relying on mutations to generate us some DNA. I recommend either pausing a lot or running on 1x or 2x speed, as there are many things to do very quickly.

Genetic Code:

  • ATP Boost - for a quick start
  • Genetic Mimic (Darwinist also works but less reliable)
  • Aquacyte - just a little extra boost to get to Greenland and the other islands
  • Urbophile - you can pick what you want here, this is my preference
  • Sympto-Stasis - though we hope for mutations, we still don't have a lot of DNA, so this helps to reduce some RNG

If a high lethality symptom is mutated, devolve it immediately until specified otherwise (until the very end). If you get a sterilization message, either restart or evolve the necessary transmission - if it's at the very start - just restart, otherwise just evolve and continue as usual.

We are going for high enough severity to have enough DNA to evolve what we want quickly

1. Start in trusty Saudi Arabia.

2. Wait for 10 DNA and evolve symptoms Rash, Sweating and Coughing.

3. Evolve symptoms Skin Lesions, Pneumonia and Sneezing - these will help spread the disease more, and help with the cold climates.

4. Pop the red bubbles, you should have quite a few of them (wait a bit if they don't appear). When you accumulated enough DNA, evolve transmissions Water 1 and Water 2. Gotta get to the islands!

5. Evolve Cysts, Hyper Sensitivity, and Abscesses for more infectivity.

6. At this point, you will like get a message that the disease is spreading. Don't worry too much about it. pop some red bubbles until you get ~40, and evolve abilities Viral Instability 1 & 2, Cold Resistance 1, Drug Resistance 1, and Genetic Hardening 1,

7. Pop more red bubbles until ~30 DNA and get Genetic Hardening 2. Get another ~20 DNA and get Cold Resistance 2,

8. At this point, most likely the cure barely started, all of Africa has been infected, most of Europe and Asia, and some of the Americas. We are on the road to success! Evolve symptom Pulmonary Fibrosis if it didn't evolve yet.

9. Store about at least 50-60 DNA, and evolve Necrosis when either

If necrosis has mutated at this point, you can either keep it or devolve until one of the conditions apply. Devolving is more reliable if you have enough DNA, otherwise keep it. Once you have Necrosis, let any symptom to mutate, don't devolve anything.

If you have a lot of DNA points at the point, you can evolve ability Viral Instability 3 - this is not necessary but definitely worth it if you have the DNA for it, this will evolve a lot of symptoms very quickly. Wait until all the countries have been infected.

10. Once all the countries have been infected (specifically, when all the islands have been infected), evolve ability Drug Resistance 2 and symptom Total Organ Failure. Now we wait and store as much DNA as possible - we want about 90-100 DNA.

11. When there are about 5k people left, evolve Genetic Reshuffle 1,2,3.

Congratulations! you should've finished in about no more than 280 days, and the cure should be no more than 40%

Strategy 2

There is a lot of wiggle-room for you to do what you wish, if you wish. If you follow the guide exactly it should work after no more than 3 times. You can change steps 5-9 if you feel like it doesn't jive with you (essentially - do what you want in the mid game, but keep enough DNA for Total Organ Failure and all the reshuffles)

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