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{{infobox
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{{infobox plague
|Box title = ''Prion''
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|title1 = ''Prion''
|image = File:Prion.png|thumb|
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|image1 = Prion.png
 
|caption = Slow, subtle and extremely complex pathogen hidden inside the brain.
|imagewidth = 300
 
 
|type = Standard
|caption = Slow, subtle and extremely complex pathogen hidden inside the brain.
 
 
|ability = [[Neural Atrophy 1|Neural Atrophy]]
|Row 1 title = Plague Type:
 
 
|cost = Complete Parasite (Normal or higher) or $0.99USD
|Row 1 info = Standard
 
 
|release = May 23, 2012, Version 1.0
|Row 2 title = Special [[Abilities|Ability]]:
 
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|infectivity = 1
|Row 2 info = [[Neural Atrophy 1|Neural Atrophy]]
 
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|severity = 1
|Row 3 title = Cost:
 
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|lethality = 0
|Row 3 info = Complete Parasite (Normal or higher) or $0.99USD
 
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|cure = 120%
|Row 4 title = Release date:
 
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|mutation 0.5
|Row 4 info = May 23, 2012, Version 1.0
 
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|air = 1
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|sea = 1
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|land = 1
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|rich = 0
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|poor = 1
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|urban = 1
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|rural = 1
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|hot = 0.1
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|cold = 0.1
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|humid = 1
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|arid = 1
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|iis = 0.05 (min 0.5)
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|sis = 0.04 (min 0.4)
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|lis = 0.01 (min 0.1)
 
}}
 
}}
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{{PageTabber|tab1 = '''General Information'''|tab2 = [[Strategy Guides/Prion|Strategy Guides]]}}
 
==Description==
 
Slow, subtle and extremely complex pathogen hidden inside the brain - it is much harder to notice and cure. Disease takes longer to react to new evolutions. 
 
 
 
==Traits==
 
==Traits==
The unique trait that Prion has in Plague Inc is [[Neural Atrophy 1|Neural Atrophy]], which is like [[Genetic Hardening 1|Genetic Hardening]], slowing down cure research. The prion also seems to spread slightly slower than most other standard plague types, and as noted in the game, the disease takes longer to react to new evolutions.
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The unique trait that Prion has in Plague Inc is [[Neural Atrophy 1|Neural Atrophy]], which is like [[Genetic Hardening 1|Genetic Hardening]], slowing down cure research. Evolved traits will take longer to take effect, thus Prion will act slower than other pathogens.
 
==Strategy==
 
''Please see [[Strategy guide/Prion|Prion Strategy Guides]].''
 
   
 
==Trivia==
 
==Trivia==
 
*Devolving Neural Atrophy will cause the cure effort to speed up, if there is any.
*Real life [[wikipedia:Prion|prions]] do not contain any DNA, being only proteins. However, in the game, there is a message "Prion DNA detected", a possible oversight by the developer.
 
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*Real life [[wikipedia:Prion|prions]] do not contain any DNA or RNA and can thus not evolve in the way typical pathogens like bacteria and viruses do. They are, effectively, only malfunctioning proteins.
*Devolving Neural Atrophy will cause the cure effort to speed up.
 
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** Additionally, in real life, Prions cannot be cured, but to keep in balance with the game it is also vulnerable to the cure like the other diseases.
*It is also implied that Prions are contagious, when in reality they do not spread unless a person has prolonged exposure to or has ingested part of the corpse of a person or animal with a prion.
 
*Prions in the real world are responsible for causing H1N1 (Mad Cow disease) , Fatal Familial Insomnia, Kuru (a fatal condition caused by eating brains, leading to uncontrollable shaking and death) and Huntington Chorea disease. They can have a time of incubation forty years or more, much longer than most other infections.
 
*A prion-like mechanism is believed to play a key role in most neurodegenerative diseases, like Alzheimer, Parkinson and SLA, in which agglomerated of atypical proteins are accumulated inside or near neurological cells, slowing leading them to death. It's strongly suspected the process begin in one point, and then slowly spread to healthy cells. However, in these diseases there is an important inflammatory response, while prions don't stimulate the immune system.
 
*Prion's disease mostly affects brain, since nervous system is the most complex out of all, and deteriorates faster than other systems. However, prions can be found also in other organs.
 
*People who practice cannibalism generally avoid eating the brain because of Kuru.
 
*Prions in reality are incurable and can be sporadic or inherited. However, treatments such as antibodies may be used to treat a prion. So the cure may actually be antibody drugs. Such evidence for cure can be found here: http://www.prionalliance.org/2014/02/04/what-are-the-potential-treatments-for-prion-disease/
 
   
 
== Stages of Evolution ==
 
== Stages of Evolution ==
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<gallery>
 
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<center>
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<div style="float: center; margin: 10px;">
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{| style="width: 205px; background:black; border: solid grey 3px;" cellspacing="5"
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| style="width: 10px; height: 10px; text-align: center;" | <gallery hideaddbutton="true" crop="true" type="slideshow" position="center">
 
pr1.png|Stage 1
 
pr1.png|Stage 1
 
pr2.png|Stage 2
 
pr2.png|Stage 2
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pr5.png|Final stage
 
pr5.png|Final stage
 
</gallery>
 
</gallery>
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|}
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</div>
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</center>
   
{{Plague types}}
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{{StandardPlagues}}
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[[pt-br:Príon]]
 
 
[[ru:Прион]]
 
[[ru:Прион]]
 
[[Category:Plague Type]]
 
[[Category:Plague Type]]

Revision as of 10:34, 4 January 2021

Template:Infobox plague

General Information Strategy Guides

Traits

The unique trait that Prion has in Plague Inc is Neural Atrophy, which is like Genetic Hardening, slowing down cure research. Evolved traits will take longer to take effect, thus Prion will act slower than other pathogens.

Trivia

  • Devolving Neural Atrophy will cause the cure effort to speed up, if there is any.
  • Real life prions do not contain any DNA or RNA and can thus not evolve in the way typical pathogens like bacteria and viruses do. They are, effectively, only malfunctioning proteins.
    • Additionally, in real life, Prions cannot be cured, but to keep in balance with the game it is also vulnerable to the cure like the other diseases.

Stages of Evolution

Standard Plague Types
Prion
Prion