Mania is a symptom in the Neurax Worm DLC and the Mad Cow Disease scenario. It triggers excess serotonin production, which leads to manic episodes. These, in turn, lead to more contact with others and an inability to focus, slowing cure research.


  • Mania is a good symptom to evolve, as both of the symptoms it unlocks are useful. Aggression leads to violence against authorities and increased infection rates, and after Obsession, the player needs only to purchase one more symptom for Transcendence, perhaps the most important symptom in the Neurax Worm campaign, to become available.
Community content is available under CC-BY-SA unless otherwise noted.