Scenario mad cow disease.png
"Panic over BSE almost shut down the beef industry in the 1990s. Imports were banned and burgers were off the menu until humanity got things under control. Recently though, unforeseen protein folding has resulted in a new variant of the prion - putting the whole food chain at risk. Is now the time to go vegetarian?"
— Plague Inc., Mad Cow Disease introduction paragraph

The Mad Cow Disease, known in-game as 'v2.CJD', is a plague type and scenario in the Mutation 1.15 update. It is one of the three scenarios that are included in the update, along with Flight Club and Where Is Everyone?. The update also emphasized this scenario in the name of "Mega Moo-Tation"

Transmissions

Avocado Pathogen spreads through consumption of avocado. Increases infectivity, especially in rich countries
Beef Pathogen spreads through consumption of beef. Increases infectivity and chance of mutation. Popular in rich countries
Broccoli Pathogen spreads through consumption of broccoli. Slightly increases infectivity
Dairy Pathogen spreads through consumption of dairy products, such as milk and cheese. Increases infectivity and chance of mutation
Fish Pathogen spreads through consumption of ocean travelling and farm raised fish stocks. Increases infectivity and chance of mutation
Frozen Storage Resilience Cell-adapted shifts in protein structure lets pathogen thrive over long food supply chains. Increases ship and plane transmission
Hermetic Storage Resilience Minor protein alterations raise chance of pathogen remaining active via long haul food suply chains. Increases ship and plane transmission
Insect (Mad Cow Disease) Pathogen spreads through (accidental) consumption of insects. Increases infectivity and chance of mutation. Especially effective in arid climates
Lamb Pathogen spreads through consumption of lamb and mutton. Increases infectivity and chance of mutation
Maize Pathogen spreads through consumption of corn products. Increases infectivity, especially in poor countries
Mango Pathogen spreads through consumption of mangos. Increases infectivity, especially in hot climates
Pork Pathogen spreads through consumption of pork. Increases infectivity and chance of mutation
Potato Pathogen spreads through consumption of potatoes. Increases infectivity, especially in cold climates
Poultry Pathogen spreads through consumption of poultry. Increases infectivity and chance of mutation
Preservative Storage Resilience Significant amino acid variances trigger rapid pathogen development when refrigerated. Increases ship and plane transmission
Rabbit Pathogen spreads through consumption of rabbit. Increases infectivity and chance of mutation. Especially effective in rural countries
Rice Pathogen spreads through consumption of rice. Greatly increases infectivity, especially in hot climates
Wheat Pathogen spreads through consumption of wheat. Increases infectivity
Wild Game Pathogen spreads through consumption of wild game. Increases infectivity across land borders and raises mutation chance

Symptoms

Evolved at start of scenario

Confusion Dopamine production stimulated to cause bouts of confusion in host. Harder to concentrate on complex work.
Dysphagia Difficulty swallowing causes occasional coughing when eating. Slight increase in infectivity.
Headache Strong headache behind the eyes causes discomfort and reduces ability to work.
Memory Loss Recent memories become nebulous in patients, replaced with vague historical recollections. Negatively impacts cure process.
Paranoia Irrational delusions and mental symptoms. Victims distrust of others makes them unlikely to seek treatment or cooperate with others.
Pins and Needles Breakdown of the nervous system causes victims to experience numbing or tingling sensations in extremities.
Psychosis Psychotic episodes lead to occasional bursts of extreme violence which can be lethal. Increases infectivity and slows future research speed.

Available to evolve at start of scenario

Acute Encephalitis Multiple inflammatory lesions in the brain triggered. Causes neurological damage resulting in death.

Available after evolving Human Cross-infection ability

Abscesses Pockets of infected flesh are painful and act as breeding grounds for the pathogen, increasing infection rates when burst.
Ataxia Cerebellum becomes vulnerable to infection, impairing victims' coordination, balance, and speech.
Blindness Primary visual cortex disconnected causing blindness. Significantly reduced awareness and causes fatal accidents.
Cannibalism Extreme Compulsion to bite or eat other humans - significantly increasing infectivity as well as lethality.
Coma Neuropathic effects in the brain stem cause loss of consciousness and sometimes death. Significantly harder to cure.
Coughing Chance of infection by spreading pathogen into surroundings. Especially in high density, urban areas.
Delirium Reduction in cognitive function causes irrationality and paranoia. Can be fatal and significantly slows future research speed.
Hallucinations Occipital lesions created, causing severe hallucinations. Lack of awareness increases transmission chance as well as risk of injury.
Inflammation Inflammation obstructs bodily processes. Swelling can obstruct breathing and be fatal.
Insanity Neuropathic action of the pathogen in the frontal lobe causes severe emotional and behavioural abnormalities. Significantly harder to cure.
Mania Excess serotonin production triggered. Manic episodes lead to increased contact with others and inability to focus.
Necrosis Large swathes of infected tissue lose blood supply and become fatal sources of gangrene. Decomposed bodies remain a vector of transmission.
Paralysis Pathogen destroys motor neurons to cause paralysis. Significantly harder to cure and lethal.
Pneumonia Serious fluid build and discharge from the lungs. People in cold climates especially vulnerable.
Pulmonary Oedema Potentially fatal heart abnormality causes breakdown of respiratory system, releasing pathogens into the air.
Seizures Random blackouts and fits reduce the patient's ability to function independently. Can be fatal
Systemic Infection Pathogen affects multiple organ and tissue types, causing body-wide infections that spread fast and can be fatal.
Total Organ Failure Catastrophic cell death of multiple tissue types causes body-wide organ failure and rapid death.

Abilities

Climate Abilities

The Climate abilities affect how good the disease is in that type of climate.

Ability Description
Cold Resistance 1 Pathogen evolves to withstand cold temperatures and climate
Cold Resistance 2 Lower intracellular water volume prevents freezing. Increased effectiveness in cold climates
Heat Resistance 1 Pathogen evolves to withstand hot temperatures and climates
Heat Resistance 2 Pathogen avoids cellular breakdown in high temperatures. Increased effectiveness in hot climates
Environmental Hardening Pathogen develops hardened coating-becoming highly weather resistant and extremely comfortable in both hot and cold climates

Medical Abilities

Drug Resistance will increase the effectiveness in richer countries. Cure resistance abilities will help slow down/decrease the percentage of the cure.

Ability Description
Genetic Hardening 1 Pathogen becomes harder to analyze in the lab. Decreases future research speed
Genetic Hardening 2 The pathogen does not reproduce in lab conditions. Decreases future research speed
Genetic ReShuffle 1 Pathogen DNA strands reassembled. More work needed to develop a cure
Genetic ReShuffle 2 A new strain of the pathogen now exists, increasing the work needed to develop a cure
Genetic ReShuffle 3 Multiple strains of the pathogen now exist, increasing the work needed to develop a cure

Plant Dissemination - Adjustments to protein folding give Prion the ability to infect plant life. Unlocks new transmissions.

Human Cross-infection - Radical folds of amino acid sequence allow prion to be transferred between humans. Unlocks new symptoms.

This is very important to the player as the base symptoms' combined lethality bar is miniscule.

Gallery

Trivia

  • Mad Cow Disease is the only scenario disease that has no Drug Resistance nor equivalent. As a slight compensation, the Transmission Traits Beef and Avocado can be effective in rich countries and you will have them from the start.
  • Plant life must be infected in order to kill vegans in the game, since vegans do not consume dairy, unlike vegetarians. However, this does not apply if you managed to infect the world before the world knew that your disease is there, since everyone will eat normally and therefore can be infected.
Scenarios in Plague Inc. and Plague Inc. Evolved
Scenario artificial organs.png Artificial OrgansScenario black death.png Black DeathScenario global health.png Created EqualScenario fake news.png Fake NewsScenario flight club.png Flight Club
Frozen Virus Scenario Logo.png Frozen VirusScenario global warming.png Global WarmingScenario develop this.png Golden AgeScenario global cooling.png Ice Age
Scenario mad cow disease.png Mad Cow DiseaseScenario opposites world.png Mirror EarthScenario nipah virus.png Nipah VirusScenario ocean piracy.png Pirate PlagueLittle helper.png Santa's Little Helper
Scenario science denial.png Science DenialScenario shut down.png Shut Down EverythingScenario smallpox.png SmallpoxScenario financial meltdown.png Sovereign Default
Scenario swine flu.png Swine FluTeleportation.png TeleportationScenario ubg.png Ultimate Board GamesScenario unknown origin.png Unknown OriginScenario volcanic ash.png Volcanic Ash
Scenario who cares.png Who CaresScenario where is everyone.png Where Is Everyone?Scenario xenophobia.png XenophobiaScenario custom.png Custom Scenarios
Unused / Upcoming Scenarios
Scenario aids.png AIDS
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