ATP BoostEdit

Get bonus DNA at the beginning (8 extra starting DNA Points).

Cytochrome SurgeEdit

Get more DNA from popping orange DNA bubbles. This is extremely useful with Parasite, where orange bubbles become the primary way of getting DNA points. Similar to Metabolic Jump and Catalytic Swich, which are for biohazard bubbles and Cure bubbles respectively.

Metabolic JumpEdit

Get more DNA from popping red, biohazard bubbles. Similar to Cytochrome Surge and Catalytic Switch, which are for popping orange bubbles and Cure bubbles respectively.

Catalytic SwitchEdit

Get bonus DNA from popping blue Cure bubbles Similar to Metabolic Jump and Cytochrome Surge, which are for gaining more DNA from popping yellow and biohazard bubbles.

Metabolic HijackEdit

Orange and red bubbles are automatically popped. This also pops colony bubbles in the Simian Flu, potentially allowing for more relaxed gameplay. It doesn't give any more DNA for popping them, though.

DarwinistEdit

This gene increases the chance of your plague mutating. The opposite of the gene Creationist. This can amplify the tendency of Virus to randomly mutate.

CreationistEdit

This gene decreases the chance of your plague mutating. The opposite of the gene Darwinist. This can inhibit the tendency of Virus to randomly mutate. It can be used to allow plagues to stay undercover for longer than usual. Viral Instability can be used to possibly override this Gene.

Genetic MimicEdit

Your plague is harder to cure. Useful for Mega-Brutal campaigns, which involve very fast cures.

Base HydrolysisEdit

Your plague can mutate Abilities, but is easier to cure. Caution is advised when considering this gene for playing at higher difficulties.

Base OxidisationEdit

Your plague can mutate transmissions, but is easier to cure. Caution is advised when considering this gene for playing at higher difficulties.

TeracyteEdit

This gene increases the chance of your plague spreading by land. This gene is useful for infecting areas with multiple countries in close proximity to one another, such as Asia.

AquacyteEdit

This gene increases chance of your plague spreading by sea. This is useful in situations where Island Countries can be particularly difficult to infect, such as Pirate Plague.

AerocyteEdit

This gene increases chance of your plague spreading by air. This is useful in situations where planes are less common than usual, such as Volcanic Ash and can boost Saudi Arabia games.

SuppressionEdit

Your plague is more likely to cross a closed land border. This is useful in bypassing situations where a plague would usually be locked out, such as shortly after discovery. This gene is particularly useful in scenarios such as Xenophobia and Shut Down Everything.

Native BiomeEdit

This gene increases infectivity of your plague in its starting country.

XerophileEdit

This gene gives your plague a bonus in arid climates. This is useful in spreading in countries with an Arid climate, such as Saudi Arabia.

HydrophileEdit

This gene gives your plague a bonus to infectivity in humid climates. This is useful in spreading in countries with a Humid climate, such as India.

RurophileEdit

This gene gives your plague a bonus to infectivity in rural environments. This is useful in spreading in Rural Countries, such as Argentina.

UrbophileEdit

This gene gives your plague a bonus in urban environments. This is useful in spreading in Urban Countries, such as China.

ExtremophileEdit

This gene gives your plague a minor bonus in all environments.

Ionised HelixEdit

This gene grants bonus DNA when devolving (+2 DNA Points for devolution). This gene is useful at lower difficulties because devolution of low-tier Symptoms, for example, frees up DNA Points that can be used to evolve higher-tier symptoms. In general, it reduces the total cost.

Translesion +Edit

Costs to devolve don't increase. This is useful with Virus and/or high difficulty modes, because of high amounts of symptoms and high costs of symptoms respectively.

Sympto-StasisEdit

Symptom costs don't increase, but your plague will be easier to cure. Caution is advised when considering the use of this gene at higher difficulties. This is a very powerful gene for all standard plagues of which it is available, as costs can skyrocket to expensive heights.

Trans-StasisEdit

Transmission costs don't increase, but your plague will be easier to cure. Caution is advised when considering the use of this plague at higher difficulties. Useful for Neurax Worm.

Patho-StasisEdit

Ability costs don't increase, but your plague will be easier to cure. Caution is advised when considering the use of this gene at higher difficulties. Useful Fungus and Bio-Weapon, because each spore bursts can be bought with 1 DNA point and Unlock Annihilate gene and Gene Compression can be bought easily respectively.

Autolytic ReductionEdit

This gene slightly decreases the speed at which zombies decay, allowing them to be dangerous for longer periods of time.

Cytopathic BoostEdit

Infected corpses are more likely to reanimate as a zombie.

ThermoNecroEdit

This gene reduces the zombie rate of decay in countries with a Hot climate. This increases the effectiveness of zombies in hot countries. Can be combined with Mummification for effectiveness.

Spliced ActivationEdit

Active abilities cost less DNA to use. This allows the player to invest more DNA Points in improving the deadliness of their zombies if they wish to do so.

Dopamine InhibitorEdit

This gene increases the chance of a zombie victim becoming a zombie.

Viral AffinityEdit

This gene increases the rate of ape-to-ape transmission.

Call of the WildEdit

Apes are less likely to be found by humans. This gene can be used to ensure the humans take a longer time to figure out that the Simian Flu is causing the apes to behave erratically.

Together StrongEdit

This gene increases DNA gained from colonies (+1 DNA).

LeadershipEdit

Active abilities cost less DNA to use (1/2 cost). This gene allows the player to invest more DNA Points into either improving their apes or negatively impacting humans.

Adrenal SurgeEdit

This gene increases ape strength and speed, but it is lethal over time. The latter portion makes this gene potentially useful in a Simian Flu

Cortisol SensitivityEdit

This gene reduces research from Gen-Sys experiments on apes. This has the effect of reducing the effectiveness of the Cure effort.

Latent CatalystEdit

This gene allows you get DNA when a Gen-Sys lab is destroyed.

Ion DeficitEdit

It costs more to devolve, but it also makes the Simian Flu harder to cure.

Ion SurgeEdit

It costs less to devolve, but the Simian Flu is easier to cure.

ATP OverdoseEdit

Bonus DNA is given at the start, but it costs significantly more to devolve (+15 starting DNA Points), (20 more points devolution cost).

Witch DoctorEdit

Vampire heals faster when in its lair

Shadow SpawnEdit

Vampire less likely to be spotted in countries with lairs

Mad ScientistEdit

All bubbles are automatically popped for you

Unholy EngineerEdit

Harder for drones to target lairs

Frugal ResearcherEdit

Lair DNA bonus triggers with fewer infected people

Healthy EaterEdit

Increases vampire maximum health

BrawlerEdit

Vampire Blood Rage ability doesn't cost DNA

• This is means blood rage ability's costs will be disabled, making it similar to Budget Bat.

HarvesterEdit

Vampire gets more DNA when consuming people using Blood Rage

ScavengerEdit

Vampire gets more DNA from destroying labs and Templar Bases

BerserkerEdit

Vampire Blood Rage ability kills more people

Bat BoltEdit

Vampire Flight range increases

Fair Weather BatEdit

Vampire flies faster when not injured

Socially Awkward BatEdit

Vampire starts Blood Rage automatically when entering a new country

• Doesn't work with Brawler.

Budget BatEdit

Vampire Flight ability doesn't cost DNA

Aerophobic BatEdit

Vampire flies faster but damages health