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Plague Inc. Wiki
General Information
Scenario black death.png "Patient Zero is infected with a previously dormant strain of Yersinia pestis from an unknown origin. Humanity must face a deadly bacterium that has hidden for centuries - previously killing over 200 million people. However, the world has changed a lot in 700 years with better hygiene and more antibiotics.
Will the disease be able to adapt and spread before its victims die off?"

— Plague Inc., Black Death introduction paragraph


The Black Death is scenario in Plague Inc.

Scenario Attributes

As a nod to its real-life counterpart, Black Death assumes the form of a Bacterium, with its real-life scientific alias Yersinia pestis as its default name.

It starts with Flea 1, Fever, Coma, Necrosis, Buboes and Bubonic plague, and these cannot be devolved.

Transmissions

Zoonotic Transmissions

These Transmissions can only be taken by first taking the 'Flea 1' trait, already evolved at the start of the game.

Trait Description
Flea 1  Common flea susceptible to infection. Increase infectivity, especially in urban regions and mutation.(Can't be devolved. You start with it)
Flea 2 Flea bites less likely to cause adverse reaction in host - increasing infectivity
Flea 3 Pathogen produces exotoxin that kills most infected fleas - reducing infectivity. However survivors resistant to synthetic insecticides.
Flea 4 Pathogen exotoxin accelerate flea life cycle - significantly reducing egg and larva susceptibility to extreme climates.
Rodent 1 Rodents directly susceptible to infection. Increase infectivity, especially in urban regions and mutation.
Rodent 2 Pathogen survives in rodent droppings. Infectivity increased, especially in urban regions.
Bird 1  Birds become susceptible to infection. Avian carriers increase infectivity, land transmission and mutation.
Bird 2 Avian brain tissue compromised causing birds to attack other species. Increases mutation, infectivity and land based transmission.
Livestock 1  Livestock suscetible to infection. Increase infectivity, especially in rural regions and mutation.
Livestock 2  Wildlife susceptible to infection. Increase infectivity, especially in rural regions and mutation.
Extreme Zoonosis Infection crosses multiple species barrier. Increase infectivity, especially in rural and urban areas, mutation chance and cross-country transmission.

Pneumonic Plague

These Transmissions can only be taken by first taking the 'Pneumonic Plague' ability, available at the start of the game.

Trait Description
Air 1  Gives pathogen ability to travel on dust particles. Increase infectivity, especially in arid environments and plane transmission.
Air 2 Gives organism ability to survive suspended in air for a long time. Increase infectivity, especially in arid environments and plane transmission.
Water 1 Pathogen can survive outside the body in fresh, warm water. Increase infectivity, especially in humid environments and ship transmission.
Water 2 Pathogen able to survive in chemically treated water. Increase infectivity, especially in humid environments and ship transmission.
Extreme Bioaerosol Pathogen bypasses air/water filters due to adaptive cellular shell. Increase infectivity, especially in humid & arid climates and plane/ship transmission.

Symptoms

Bubonic Symptoms

These Symptoms are available at the start of the game.

Trait Description
Rash The skin becomes blistered and painful, slightly increasing infectivity.
Cysts Painful lumps containing pockets of the pathogen. Slight chance of bursting which can spread disease.
Sweating The loss of fluid through sweating also increases infection rates due to poor hygiene. More dangerous in cold countries.
Hyper sensitivity Increases likelihood of allergic reactions which can distract the immune system. Rich regions particularly vulnerable.
Fever Increase in temperature, contagiousness and severe dehydration which can be fatal. (Can't be devolved. Already evolved from the start)
Inflammation Inflammation obstructs bodily processes. Swelling can obstruct breathing and be fatal.
Immune Suppression Pathogens attach to lymphocytes, suppressing immune system and allowing significantly greater freedom of mutation. Can be lethal.
Skin Lesions Breakdown in the epidermis causes large open wounds which significantly increase infectivity.
Seizures Random Blackouts and fits reduce the patient's ability to function independently. Can be lethal.
Paralysis Pathogen destroys motor neurons to cause paralysis. Significantly harder to cure and can be lethal.
Necrosis Large swathes of infected tissue lose blood supply and become fatal source of gangrene. Decomposed bodies remain a vector of transmission. (Can't be devolved. Already evolved from the start)
Coma Neuropathic effects in the brain stem cause loss of consciousness and sometimes death. Significantly harder to cure. (Can't be devolved. Already evolved from the start)
Buboes Infected lymph nodes become swollen and inflamed. Bursting can aerosolise contents and infect others. (Can't be devolved. Already evolved from the start)

Pneumonic Symptoms

These Symptoms can only be taken by first taking the 'Pneumonic Plague' ability, available at the start of the game.

Trait Description
Coughing Chance of infection by spreading pathogen into surroundings, especially in high density urban areas.
Pneumonia Serious fluid build and discharge from the lungs. People in cold climates especially vulnerable.
Sneezing Fluid discharge through sneezing greatly increases infection rates.
Pulmonary Oedema Potentially fatal heart abnormality causes breakdown of respiratory system, releasing pathogen into the air.
Haemoptysis Coughing up blood from inflamed bronchi increases infectivity and is fatal in extreme cases.

Septicemic Symptoms

These Symptoms can only be taken by first taking the 'Septicemic Plague' ability, available at the start of the game.

Trait Description
Nausea Irritated stomach lining leads to discomfort. Slight chance of infection when kissing.
Vomiting The expulsion of infected material through projectile vomiting increases the risk of infection.
Hypotension Low blood pressure deprives organs of oxygen and nutrients, increasing severity and causing profound fatigue.
Abscesses Pockets of infected flesh are painful and act as breeding grounds for the pathogen, increasing infection rates when burst.
Internal Haemorrhaging Arterial membranes break down, causing rapid internal bleeding and death.
Diarrhoea Pathogen active in digestive tract, causing infection through faeces and potentially lethal dehydration. Poor countries very vulnerable.
Hemorrhagic Shock Severe loss of blood volume causes oxygen deprivation, loss of consciousness and death.
Systemic Infection Pathogen affects multiple organs and tissue types, causing body-wide infections that spread fast and can be lethal
Dysentery A complete breakdown in the digestive system causes infected sewage, dehydration, starvation and death.
Total Organ Failure Catastrophic cell death of multiple tissue types causes body-wide organ failure and rapid death.

Abilities

Climate Abilities

These abilities will affect the plague in different countries, climates and temperatures.

Trait Description
Cold Resistance 1 Pathogen evolves to withstand cold temperatures and climates.
Cold Resistance 2 Lower intracellular water volume prevents freezing. Increased effectiveness in cold climates
Heat Resistance 1 Pathogen evolves to withstand hot temperatures and climates
Heat Resistance 2 Pathogen avoids cellular breakdown in high temperatures. Increased effectiveness in hot climates.
Environmental Hardening Pathogen develops hardened coating - becoming highly weather resistant and extremely comfortable in both hot and cold climates.

Cure/Drug Resistance Abilities

These abilities will affect the plague's resistance against treatments and drugs. They will also slow down cure creation speed and increase more work required to create a cure.

Trait Description
Drug Resistance 1 Pathogen becomes resistant to class 1 and 2 antibiotics. Increase effectiveness in wealthy countries.
Drug Resistance 2 Pathogen develops resistance to class 3 and 4 antibiotics. Increase effectiveness in wealthy countries.
Drug Resistance 3 Pathogen highly resistant to all known antibiotics. Harder to develop cure. 
Genetic Hardening 1 Pathogen becomes harder to analyse in the lab. Decreases future research speed.
Genetic Hardening 2 The pathogen does not reproduce in lab conditions. Decreases future research speed.
Genetic ReShuffle 1 Pathogen DNA strands reassembled. More work needed to develop a cure.
Genetic ReShuffle 2 A new strain of the pathogen now exists, increasing the work needed to develop a cure.
Genetic ReShuffle 3 Multiple strains of the pathogen now exists, increasing the work needed to develop a cure.
Hardened Reshuffle 1 Pathogen DNA structure reassembled and highly unstable. Significantly harder to develop cure and also slows research speed.
Hardened Reshuffle 2 Pathogen DNA structure reassembled and highly unstable. Significantly harder to develop cure and also slows research speed.

Unique Abilities

These are abilities exclusive to the plague, Black Death.

Trait Description
Pneumonic plague Gain ability to infect respiratory system and develop pneumonic form of plague. Airborne and virulent.
Bubonic plague Gain ability to infect lymphatic system and develop bubonic form of plague. Zoonotic and lethal.
Septicemic plague Gain ability to infect the blood stream and develop septicemic form of plague. Rare and very lethal.

Gallery

Scenarios in Plague Inc. and Plague Inc. Evolved
Scenario artificial organs.png Artificial OrgansScenario black death.png Black DeathScenario global health.png Created EqualScenario fake news.png Fake NewsScenario flight club.png Flight Club
Frozen Virus Scenario Logo.png Frozen VirusScenario global warming.png Global WarmingScenario develop this.png Golden AgeScenario global cooling.png Ice Age
Scenario mad cow disease.png Mad Cow DiseaseScenario opposites world.png Mirror EarthScenario nipah virus.png Nipah VirusScenario ocean piracy.png Pirate PlagueLittle helper.png Santa's Little Helper
Scenario science denial.png Science DenialScenario shut down.png Shut Down EverythingScenario smallpox.png SmallpoxScenario financial meltdown.png Sovereign Default
Scenario swine flu.png Swine FluTeleportation.png TeleportationScenario ubg.png Ultimate Board GamesScenario unknown origin.png Unknown OriginScenario volcanic ash.png Volcanic Ash
Scenario who cares.png Who CaresScenario where is everyone.png Where Is Everyone?Scenario xenophobia.png XenophobiaScenario custom.png Custom Scenarios
Unused / Upcoming Scenarios
Scenario aids.png AIDS
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